Order Provera tablets online from a U.S. pharmacy (prescription required)

Product Name	Provera (oral)
Dosage	2.5 mg, 5 mg, 10 mg tablets (USA)
Active Ingredient	Medroxyprogesterone acetate
Form	Oral Tablets (prescription only in the USA)
Description	A progestin used for abnormal uterine bleeding due to hormonal imbalance, secondary amenorrhea, and to reduce the risk of endometrial hyperplasia during estrogen therapy.
How to Order in the USA	With a valid prescription or through a same‑day telehealth evaluation

Provera (medroxyprogesterone acetate) is a well‑established progestin medicine in the United States. Unlike over‑the‑counter products, Provera tablets are prescription medications that are dispensed under the supervision of a U.S.‑licensed healthcare provider. In the USA, common oral strengths are 2.5 mg, 5 mg, and 10 mg. These tablets are typically used for three main purposes: managing abnormal uterine bleeding related to hormonal imbalance, treating secondary amenorrhea, and reducing the risk of endometrial hyperplasia in postmenopausal patients who are using systemic estrogen therapy.

In everyday gynecologic practice, Provera is valued for its predictable progestational effect on the endometrium, its flexible dosing schedules, and its suitability across different clinical scenarios—from short cyclic courses that induce withdrawal bleeding to continuous low‑dose regimens that protect the endometrium during hormone therapy. In the USA, medroxyprogesterone acetate is also available as a long‑acting injection for contraception (commonly known as Depo‑Provera). However, the oral tablet form discussed on this page is not indicated as a stand‑alone contraceptive product; it is primarily prescribed for the indications outlined above.

If you are exploring whether Provera is right for you, a clinician will typically review your medical history, rule out pregnancy, consider structural or systemic causes of bleeding, and confirm that a progestin‑based treatment is appropriate. U.S. pharmacies can dispense the medicine after a valid prescription is issued. Many patients obtain Provera via local retail chains and health system pharmacies, as well as through mail‑order options that serve all 50 states.

Provera cost in the USA

Pricing for Provera (medroxyprogesterone acetate) tablets varies by pharmacy, dose, quantity, and whether you are filling brand‑name or generic. In the U.S., most prescriptions are filled as the FDA‑approved generic, which significantly reduces out‑of‑pocket cost for cash‑pay patients and those with high deductibles.

To give a general idea, typical cash prices for generic medroxyprogesterone acetate 10 mg tablets can range from about $7 to $25 for 30 tablets at large U.S. retail pharmacies when using widely available discount programs. The 2.5 mg and 5 mg strengths are also commonly priced within an affordable range, though exact costs depend on your location, insurance, and the dispensing pharmacy’s pricing policy.

Brand‑name Provera may cost more, and your copay will depend on your specific insurance formulary and tier. If you are prescribed a cyclic regimen (for example, 10 to 14 days of tablets each month), a 30‑count bottle may last several months, potentially lowering monthly costs. For continuous daily dosing, your provider can coordinate an appropriate supply with refills to maintain steady coverage. Always check real‑time pharmacy pricing and your plan benefits for the most accurate estimate.

Ways to save in the USA include using pharmacy discount cards, checking mail‑order options, asking your pharmacist if a lower‑cost strength can be used with tablet splitting (only if appropriate and approved by your prescriber), and verifying formulary coverage. Your healthcare provider or pharmacist can help you compare options in your area.

Where can I buy Provera in the USA?

In the United States, Provera tablets are available only with a valid prescription. You can have your prescription filled at major retail pharmacies (such as CVS, Walgreens, Rite Aid, Walmart, and regional chains), independent community pharmacies, hospital‑based pharmacies, or via licensed mail‑order services. Many people appreciate the convenience of online pharmacies and home delivery, particularly when using ongoing cyclic or continuous regimens.

If you do not yet have a prescription, you can schedule a visit with your primary care clinician, OB/GYN, or a licensed telehealth provider who can evaluate your symptoms, review your medical history, and determine whether Provera is appropriate. After your prescription is issued, it can be sent electronically to the U.S. pharmacy of your choice for fulfillment and shipping or pickup.

Our partner pharmacy network supports prescription processing across the USA and offers discreet packaging, shipment tracking, and customer support. Orders are handled in compliance with U.S. regulations. If you are transitioning from another progestin therapy or starting hormone therapy with estrogen, your provider will help select a dose and schedule that best fits your health goals.

Provera USA: how to get started

Getting Provera in the U.S. is straightforward:

1. Consultation: Meet with a U.S.‑licensed clinician (in person or via telemedicine) to discuss your symptoms and history. Pregnancy and other causes of abnormal bleeding should be excluded.
2. Prescription: If Provera is appropriate, your clinician will prescribe the correct strength and dosing schedule (cyclic or continuous).
3. Fulfillment: Choose your preferred U.S. pharmacy—local retail or mail‑order—and have your prescription sent there. Many pharmacies support fast home delivery nationwide.

What is Provera (medroxyprogesterone acetate)?

Provera is a synthetic progestin that acts similarly to the natural hormone progesterone. In gynecologic care, it transforms and stabilizes the endometrium (the lining of the uterus), which helps regulate menstrual cycles, control dysfunctional uterine bleeding due to hormonal imbalance, and protect the endometrium from unopposed estrogen stimulation in postmenopausal patients on hormone therapy.

In the USA, oral Provera is most commonly prescribed in 2.5 mg, 5 mg, and 10 mg tablet strengths. Dosing schedules vary depending on the indication. For example, a cyclic 10 mg daily regimen for 10 to 14 days per month may be used to induce predictable withdrawal bleeding. By contrast, a continuous low‑dose approach may be selected to oppose estrogen in hormone therapy and reduce the risk of endometrial hyperplasia.

It is important to note that oral Provera tablets are not the same as the long‑acting injectable form (medroxyprogesterone acetate 150 mg intramuscular), which is indicated for contraception. The oral product discussed here is not indicated as a stand‑alone birth control method.

Provera for abnormal uterine bleeding (AUB)

Abnormal uterine bleeding due to hormonal imbalance is a common reason clinicians prescribe Provera. After appropriate evaluation to exclude pregnancy, structural causes (such as fibroids, polyps), systemic conditions (thyroid disease, coagulopathies), and medication effects, a progestin course can help stabilize the endometrium and restore more predictable bleeding patterns.

A commonly used regimen in the USA is 10 mg by mouth once daily for 10 to 14 days per cycle, often starting on day 16 to 21 of the cycle depending on the clinical scenario. A withdrawal bleed typically occurs within several days after the last tablet. Your clinician may tailor the schedule to your individual cycle pattern and goals. For some patients, repeating cyclic therapy over multiple months helps retrain the cycle and reduces unscheduled bleeding.

People with heavy or prolonged bleeding should seek medical evaluation promptly, as additional therapies (or diagnostics such as ultrasound or endometrial sampling) may be warranted. Your clinician will work with you to choose the safest and most effective plan, which may include Provera alone or in combination with other treatments.

Why Provera matters in AUB care

For many patients, progestin therapy offers a non‑surgical option to control bleeding and improve quality of life. By transforming a proliferative endometrium into a secretory one, Provera promotes orderly shedding when the medication is stopped, reducing the unpredictability of bleeding. It can be used as an initial therapy, a bridge while other causes are being addressed, or as part of a long‑term management plan when appropriate. Individualized care is key, especially for patients with comorbidities or those taking other medications that may influence bleeding.

Provera for secondary amenorrhea

Secondary amenorrhea refers to the absence of menstrual periods in someone who previously had regular cycles. The reasons can range from pregnancy and hormonal disturbances to stress, weight changes, thyroid disease, or hyperprolactinemia. After the clinician excludes pregnancy and evaluates for underlying causes, Provera is often used in a short course to induce a withdrawal bleed and assess estrogen status (sometimes called a “progestin challenge test”).

In the USA, a standard approach is 10 mg orally once daily for 5 to 10 days. If bleeding occurs within several days after completing the course, it suggests that adequate endogenous estrogen was present and that the amenorrhea may be related to anovulation. Your clinician will interpret the result in context and advise on next steps, which may include cycle regulation plans, further endocrine evaluation, or other targeted therapies.

Is Provera a contraceptive?

Oral Provera tablets are not indicated as contraception in the USA. The injectable form of medroxyprogesterone acetate (often called Depo‑Provera) is a contraceptive given every three months. If pregnancy prevention is a goal, speak with your clinician about appropriate options, including combined oral contraceptives, progestin‑only pills, long‑acting reversible contraception (IUDs, implants), or the injectable form when suitable.

Provera with estrogen therapy (endometrial protection)

In postmenopausal patients using systemic estrogen therapy, adding a progestin like Provera reduces the risk of endometrial hyperplasia and endometrial cancer associated with unopposed estrogen. U.S. regimens may be cyclic or continuous:

• Cyclic: 5 to 10 mg daily for 12 to 14 days of each 28‑day cycle, typically resulting in predictable withdrawal bleeding.
• Continuous: 2.5 mg daily in combination with continuous estrogen therapy, often with the goal of minimizing bleeding over time.

The choice between cyclic and continuous use depends on patient preference, bleeding tolerance, and clinical considerations. Your clinician will tailor the regimen, monitor response, and adjust therapy as needed.

Provera for endometriosis and other off‑label uses

Some clinicians consider progestins like medroxyprogesterone acetate for endometriosis‑related pain when other therapies are not suitable or tolerated. By suppressing endometrial tissue growth, progestins may reduce pain and bleeding. However, dosing and duration must be carefully individualized, and alternative agents (such as oral contraceptives, levonorgestrel‑IUD, or GnRH analogs) may be preferred depending on patient goals and side‑effect profiles.

In oncology, higher doses of progestins have been used in palliative settings for certain cancers under specialist supervision. Those regimens differ from the gynecologic doses described here and require close monitoring. Always rely on your oncologist’s guidance for cancer‑related therapy.

How Provera works

Medroxyprogesterone acetate binds to progesterone receptors in target tissues and exerts progestational effects. In the endometrium, it converts a proliferative lining to a secretory state and, when withdrawn, triggers shedding. It also decreases pituitary gonadotropin secretion, which can inhibit ovulation in some contexts and reduce endometrial stimulation by estrogen. The net effect is improved cycle control and endometrial protection when clinically indicated.

Safety profile and boxed warnings

All hormones, including progestins, must be used thoughtfully. When Provera is combined with estrogen in postmenopausal hormone therapy, the U.S. prescribing information includes boxed warnings about increased risks of cardiovascular events (such as heart attack and stroke), venous thromboembolism (DVT/PE), breast cancer, and probable dementia in certain older populations. Hormone therapy should be individualized, using the lowest effective dose for the shortest duration consistent with treatment goals, and reassessed regularly.

Provera is contraindicated in pregnancy, undiagnosed abnormal genital bleeding, known or suspected breast cancer, active or history of thromboembolic disease or stroke, significant liver disease, and known hypersensitivity to the drug. A clinician will review your history to ensure safe use.

Dosing guidance and schedules

Dosing is individualized. Common U.S. examples include:

• Secondary amenorrhea: 10 mg by mouth once daily for 5 to 10 days.
• Abnormal uterine bleeding (due to hormonal imbalance): 10 mg by mouth once daily for 10 to 14 days per cycle.
• Endometrial protection (postmenopausal estrogen therapy): 5 to 10 mg daily for 12 to 14 days of a 28‑day cycle, or 2.5 mg daily continuously with estrogen.

Always follow your prescriber’s instructions. Your schedule may differ based on your diagnosis, response to therapy, and overall health profile. If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose. Do not double up without your clinician’s advice.

Provera dosing: practical tips

Taking Provera at the same time each day may improve adherence and cycle predictability. It can be taken with or without food. Keep a calendar of when you take your tablets and when bleeding occurs; share this with your prescriber during follow‑up. If bleeding is heavy, prolonged, or occurs at unexpected times, contact your clinician promptly. Some people may require dose adjustments or additional evaluation.

Abnormal uterine bleeding: example regimens

For dysfunctional bleeding linked to anovulation or luteal phase deficiency, many U.S. clinicians prescribe 10 mg daily for 10 to 14 days. When the course is completed, a withdrawal bleed often follows. Your clinician may recommend repeating this each month for several cycles to reestablish a pattern, or they may select an alternative schedule aligned with your cycle length. If bleeding is due to other causes (such as fibroids), Provera may be part of a broader plan or may be less effective on its own. Diagnostic imaging and other labs may be appropriate.

Endometrial protection during estrogen therapy

For patients using systemic estrogen therapy, adding Provera helps counter the proliferative effects of estrogen on the endometrium. Two general strategies are used:

• Cyclic regimens (5–10 mg daily for 12–14 days per 28‑day cycle) typically cause scheduled bleeding after the progestin phase.
• Continuous combined regimens (2.5 mg daily) aim for minimal or no bleeding over time. Transient spotting may occur during the first months of therapy.

Regular follow‑up is recommended to assess symptom control, bleeding patterns, safety, and ongoing need for therapy. Report any unexpected or persistent bleeding to your clinician for evaluation.

How to take Provera

Take Provera exactly as prescribed. Swallow tablets with water, with or without food. If your regimen is cyclic, start and stop on the dates directed by your clinician. If your regimen is continuous, take the prescribed dose daily without interruption unless your clinician directs otherwise. Do not share prescription medications, and never change your dosing schedule without medical advice.

Pregnancy and breastfeeding

Provera is contraindicated during pregnancy and should not be used if you are pregnant or may become pregnant. Before initiating therapy, your clinician will typically confirm that you are not pregnant, especially if your periods are irregular. If you become pregnant while taking Provera, stop the medication and contact your clinician.

Medroxyprogesterone acetate may pass into breast milk. Progestin‑only methods are often considered compatible with breastfeeding, but the risks and benefits depend on dose, timing postpartum, and individual clinical factors. Talk with your pediatrician and obstetrician/gynecologist to determine the safest approach for you and your baby.

Pharmacist’s tips for using Provera

• Take your tablets at the same time each day to keep on schedule. • Track bleeding and any side effects. • If heavy bleeding, severe pain, sudden shortness of breath, chest pain, severe headache, vision changes, or jaundice occur, seek care promptly. • If using Provera with estrogen therapy, keep up with routine screening (mammograms, clinical breast exams, and gynecologic evaluations) as recommended by your clinician.

Tell your healthcare provider about all medicines and supplements you take, including over‑the‑counter products and herbal remedies. Some drugs can reduce Provera’s effectiveness or increase side‑effect risk.

Safety precautions

Do not use Provera if you have any of the following unless your clinician specifically advises otherwise:

• Pregnancy or suspected pregnancy
• Undiagnosed abnormal genital bleeding
• Active or history of deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, or myocardial infarction
• Known or suspected breast cancer or hormone‑sensitive malignancy
• Severe liver disease or liver tumors
• Hypersensitivity to medroxyprogesterone acetate or any tablet component

Use caution and discuss risks if you smoke, are over age 35, have migraine with aura, hypertension, diabetes with vascular disease, hyperlipidemia, obesity, or a strong family history of thromboembolism. Your clinician will help weigh benefits and risks and may recommend additional monitoring.

Provera side effects

Like all medicines, Provera can cause side effects. Many are mild and improve with time as your body adjusts. Commonly reported effects include:

• Changes in bleeding pattern (breakthrough bleeding, spotting, or missed periods)
• Breast tenderness
• Headache
• Nausea or bloating
• Mood changes or irritability
• Fluid retention or mild weight changes
• Dizziness or fatigue

Serious but less common side effects include blood clots (DVT/PE), stroke, heart attack, vision changes (including retinal thrombosis), significant elevation in blood pressure, jaundice or other signs of liver dysfunction, and severe allergic reactions. Seek urgent medical care if you experience warning signs such as chest pain, sudden shortness of breath, slurred speech, limb weakness, severe headache, vision loss, leg swelling/pain, or yellowing of the skin or eyes.

Side effects by clinical use case

Depending on why Provera is prescribed and how it is dosed, you may notice different patterns:

• For abnormal uterine bleeding: breakthrough spotting can occur in the first cycle(s). Withdrawal bleeding is expected after completing a cyclic course.
• For secondary amenorrhea: cramping or predictable withdrawal bleeding may occur after stopping a short course.
• For estrogen therapy (endometrial protection): spotting can occur initially, particularly with continuous regimens, and may lessen over time; report persistent or heavy bleeding.

Keep a record of your experience and share it with your clinician at follow‑up to guide any dose adjustments.

Reporting side effects

If you experience any side effects, contact your prescriber or pharmacist. In the USA, you may also report side effects to the FDA MedWatch program at 1‑800‑FDA‑1088 or online at www.fda.gov/medwatch.

Interaction of Provera with other medicines

Medroxyprogesterone acetate is metabolized in part by hepatic enzymes. Certain drugs can decrease its effectiveness or increase side‑effect risk. Always tell your clinician and pharmacist about all medications and supplements you take.

Examples of potential interactions include:

• Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin, phenobarbital, primidone, topiramate, St. John’s wort) may lower progestin levels and reduce effectiveness.
• CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, grapefruit juice in large amounts) may increase exposure.
• Anticoagulants (e.g., warfarin): hormone therapy can sometimes affect clotting parameters; monitoring may be needed.
• Other hormones or hormone‑modulating therapies: combined effects should be reviewed by your clinician.

This list is not exhaustive. Provide a complete and updated medication list to every healthcare provider you see. Your pharmacist can check for interactions at each refill.

Recommendations from our specialists

If you and your clinician decide that Provera is appropriate, consider setting reminders for cyclic or continuous dosing, keep a bleeding diary, and schedule follow‑up to reassess your response. If you are starting estrogen therapy, discuss the pros and cons of cyclic versus continuous progestin schedules. Our pharmacy partners support fast, discreet shipping throughout the USA once a valid prescription is on file. Reach out to us if you need help coordinating refills, understanding your dosing plan, or exploring cost‑saving options.

Ready to take control of your cycle? Order Provera today

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Thousands of patients rely on professional guidance and timely delivery to stay on track with therapy. When you are ready, we are here to help coordinate your prescription and get Provera delivered to your door.

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